
Thermo Fisher Scientific p19 INK4d Recombinant Superclonal Antibody (14HCLC)
Recombinant Superclonal™ Rabbit IgG antibody recognizing human p19 INK4d. High sensitivity and reproducibility with polyclonal-like performance. Validated for WB and IP. Suitable for research use in cell cycle regulation studies.
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- 710851
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunoprecipitation (IP) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 14HCLC |
| Immunogen | Peptide corresponding to Human p19 INK4d (aa 1–166) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532773 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Rat, and Mouse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple different recombinant monoclonal antibodies, providing the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, and consistent lot-to-lot reproducibility. Functionally similar to polyclonal antibodies, they recognize multiple epitopes on the target and offer enhanced detection sensitivity for low-abundance targets. Each recombinant Superclonal™ antibody contains a defined mixture of light and heavy chains, eliminating biological variability typical of traditional polyclonal antibody production.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The product and performance remain unchanged.
Target Information
p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. It forms a stable complex with CDK4 or CDK6, preventing activation of CDK kinases and regulating cell cycle G1 progression. Expression of p19 oscillates in a cell-cycle dependent manner, lowest at mid-G1 and highest during S phase. It plays a role in repressing neuronal proliferation and spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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