Thermo Fisher Scientific delta Catenin Monoclonal Antibody (SP63)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100

-

Immunocytochemistry (ICC/IF)

1:2,000

View 1 publication 1 publication

Flow Cytometry (Flow)

1:250

-

Product Specifications

Species Reactivity

Human

Published species

Dog

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

SP63

Immunogen

Synthetic peptide from the C-terminus of human p120 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:delta Catenin,uniProtId:O60716-1,ncbiNodeId:9606,antigenRange:968,antigenLength:968,antigenImageFileName:MA5-16386_delta_Catenin_O60716-1_Rabbit.svg,antigenImageFileNamePDP:MA5-16386_delta_Catenin_O60716-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.022 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.6, with 1% BSA

Contains

0.1% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2537905

Product Specific Information

Heat-mediated antigen retrieval is recommended prior to staining, using an EDTA buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is breast carcinoma.

Target Information

Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.