Thermo Fisher Scientific delta Catenin Monoclonal Antibody (SP63)
인간 delta Catenin을 인식하는 Rabbit monoclonal antibody (Clone SP63). IHC, ICC/IF, Flow Cytometry에 사용 가능. Protein A/G로 정제된 액상 형태로 제공되며, 안정적 PBS buffer에 보존. 세포 접착 및 신호전달 연구에 적합.
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Thermo Fisher Scientific delta Catenin Monoclonal Antibody (SP63)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:2,000 | View 1 publication |
| Flow Cytometry (Flow) | 1:250 | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Dog |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SP63 |
| Immunogen | Synthetic peptide from the C-terminus of human p120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.022 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.6, with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537905 |
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining, using an EDTA buffer (pH 6.0) for 10 minutes followed by cooling at room temperature for 20 minutes.
Following antigen retrieval, incubate samples with primary antibody for 30 minutes at room temperature.
A suggested positive control is breast carcinoma.
Target Information
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1, and ERBB2 receptors.
The association of catenins to cadherins produces a complex linked to the actin filament network, which is crucial for cadherins’ cell-adhesion properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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