Thermo Fisher Scientific PD-L1 (CD274) Chimeric Recombinant Human Monoclonal Antibody (XGMHc25.1)
인간 PD-L1(CD274)을 인식하는 키메라 재조합 단일클론 항체. IHC 및 유세포분석에 사용 가능. HEK293 세포에서 발현된 Human IgG1, kappa 형식. Protein A로 정제된 액상 항체로, 4°C 단기보관 및 -20°C 장기보관 권장.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | XGMHc25.1 |
| Immunogen | The original antibody was generated by immunizing BALB/c mice with a human B7-H1 fusion protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody binds human PD-L1.
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. Its receptor, PD-1, negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be up-regulated by IFN-gamma stimulation. PD-L1 may play an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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