Thermo Fisher Scientific PDE4A Monoclonal Antibody (OTI1E3), TrueMAB
인간 PDE4A 단백질을 인식하는 단클론 항체로, Western blot과 면역세포염색에 최적화됨. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도로 사용 가능. 신호전달 연구 및 PDE 관련 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:3000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Full length human recombinant protein of human PDE4A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Cyclic nucleotides act as second messengers regulating numerous cellular responses to extracellular signals such as hormones, light, and neurotransmitters.
Cyclic nucleotide phosphodiesterases (PDEs) control cellular concentrations of cyclic nucleotides, contributing to signal transduction processes.
PDE4A is a class IV cAMP-specific phosphodiesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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