Thermo Fisher Scientific Phospho-Rb (Ser608) Monoclonal Antibody (51B7)
Rb 단백질의 Ser608 인산화 형태를 검출하는 단일클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Human, Mouse, Rat 시료에서 검증됨. 0.2 mg/mL 액상 형태로 4°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | – | View 3 publications |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 51B7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10944063 |
Product Specific Information
This antibody was originally validated as part of a Thermo Scientific Cellomics High Content Screening Kit. The antibody sold separately may have slightly different performance and may need to be further optimized for the best results.
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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