Thermo Fisher Scientific STAT6 Recombinant Rabbit Monoclonal Antibody (SY02-72)
STAT6 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot, IHC, ICC, IP 등 다양한 응용에 적합. 인간 및 생쥐 반응성, 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- MA545032
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific STAT6 Recombinant Rabbit Monoclonal Antibody (SY02-72)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SY02-72 |
| Immunogen | Synthetic peptide within human STAT6 C terminal |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931486 |
Target Information
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL-13. STAT6-deficient (Stat6-/-) models show impaired IL-4-mediated functions, including Th2 helper T-cell differentiation, surface marker expression, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4-mediated proliferation. STAT6 mRNA is expressed in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta. STAT6 plays a crucial role in Th2 immune response and IL-4-mediated biological activities, existing in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: MA5-45032_STAT6_P42226-1_Rabbit.svg, MA5-45032_STAT6_P42226-1_Rabbit_PDP.jpeg)
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