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Thermo Fisher Scientific SARS-CoV/SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (CR3022)
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Thermo Fisher Scientific

Thermo Fisher Scientific SARS-CoV/SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (CR3022)

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SARS-CoV 및 SARS-CoV-2 스파이크 단백질 S1 도메인에 결합하는 인간 재조합 단일클론 항체. 다양한 in vitro 분석 및 ELISA, SPR 등에 사용 가능. HEK293 세포 발현, IgA1 아이소타입, 비결합형 액상 형태로 제공. 연구용으로만 사용.

브랜드
Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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마지막 업데이트 2025. 07. 23. 오후 07:32
Thermo Fisher Scientific MA551598 SARS-CoV/SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (CR3022) 50 ug pk판매 단위 pk
재고 1개
1,121,200원VAT 포함 1,233,320원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific SARS-CoV/SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (CR3022)

Applications

Immunocytochemistry (ICC/IF)

  • Tested Dilution: Assay-dependent

ELISA

  • Tested Dilution: Assay-dependent

Neutralization (Neu)

  • Tested Dilution: Assay-dependent

In vitro Assay (IV)

  • Tested Dilution: Assay-dependent

Surface Plasmon Resonance (SPR)

  • Tested Dilution: Assay-dependent

Product Specifications

항목 내용
Species Reactivity Virus
Host / Isotype Human / IgA1, kappa
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone CR3022
Immunogen The original monoclonal antibody was generated through an scFv library derived from peripheral blood lymphocytes of a patient exposed to SARS-CoV.
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS
Contains 0.02% ProClin 300
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice

Product Specific Information

This antibody binds the amino acids 318–510 in the S1 domain of the SARS-CoV Spike protein as well as SARS-CoV-2 (COVID-19) Spike protein. It also binds to P462L-substituted S318–510 fragments of the SARS spike protein.

Target Information

The SARS-CoV-2 virus, responsible for the COVID-19 pandemic, has a spike protein composed of two subunits, S1 and S2.

  • The S1 subunit binds to the human ACE2 receptor, initiating viral entry and host cell recognition.
  • The SARS-CoV S1 protein, which mediated ACE2 binding during the 2002–2003 SARS outbreak, shares high similarity with SARS-CoV-2 S1, though sequence differences may affect binding affinity.
  • Both spike proteins have a trimeric structure, with each subunit containing two domains: the N-terminal domain (NTD) and the receptor-binding domain (RBD).
  • The RBD binds directly to the ACE2 receptor, while the NTD participates in recognition of other host factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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