Thermo Fisher Scientific GRK3 Recombinant Rabbit Monoclonal Antibody (10O6S3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

10O6S3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 589-688 of human GRK3 (P35626). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRK3,uniProtId:P35626-1,ncbiNodeId:9606,antigenRange:589-688,antigenLength:688,antigenImageFileName:MA5-42913_GRK3_P35626-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42913_GRK3_P35626-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.45 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912054

Product Specific Information

Positive test controls include: Jurkat, SH-SY5Y.

Immunogen sequence: EWRGEGESRQ NLLTMEQILS VEETQIKDKK CILFRIKGGK QFVLQCESDP EFVQWKKELN ETFKEAQRLL RRAPKFLNKP RSGTVELPKP SLCHRNSNGL

Target Information

ADRBK2, or adrenergic beta receptor kinase 2 is a serine/threonine kinase that is thought to act as a regulator of receptor function. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.