Thermo Fisher Scientific Phospho-RSK3 (Thr356, Ser360) Polyclonal Antibody
RSK3 단백질의 Thr356 및 Ser360 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 사용 가능하며 Human, Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로 안정적인 보관 및 재현성 높은 신호 제공.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide corresponding to residues around human RSK3 (phospho Thr356/Ser360) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792938 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%).
- Positive Control: Neuro2A, NIH-3T3, Raw264.7, C2C12, NIH-3T3 (starvation for 16 hr), NIH-3T3 (starvation for 16 hr and 100 ng/ml PDGF treatment for 5 min), EGF treated A431.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It is believed that RPS6KA2 acts as a signal-transducing intermediate in the cellular response to several growth factors. It is expressed in many tissues, with higher levels in lung and skeletal muscle. The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may have a tonic regulation on G-protein coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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