Thermo Fisher Scientific TRAF6 Polyclonal Antibody, FITC
TRAF6 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, Immunoprecipitation 등 다양한 응용에 적합합니다. 인간 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence on TRAF6 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are adaptor proteins that link the TNF receptor superfamily to signaling pathways, regulating cell death and stress responses. TRAF proteins share a conserved homology region allowing receptor and TRAF–TRAF interactions, activating various signal cascades.
TRAF2 and TRAF3 bind directly to CD40, a NF receptor superfamily member crucial for NF‑κB activation in B lymphocytes. TRAF2 and TRAF6 are required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with lymphotoxin‑beta receptor (LTβR) along with TRAF3 and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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