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Thermo Fisher Scientific TICAM2 Polyclonal Antibody, Biotin
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TICAM2(TRAM) 단백질을 인식하는 Biotin 결합 다클론 항체로, Western blot, ELISA, IP, Dot blot에 적합합니다. Rabbit에서 생산된 IgG 항체이며, 인체·생쥐·랫드에 반응합니다. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공합니다.
- 판매단위
- pk
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594,400원VAT 포함 653,840원
Thermo Fisher Scientific · Thermo Fisher Scientific TICAM2 Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Dot Blot (DB) | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequences on TRIF-related adapter molecule |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to the MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstitutes LPS-induced Trif-dependent NF-κB activation and CXCL10 promoter activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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