Thermo Fisher Scientific Ephrin A5 Polyclonal Antibody
인간 Ephrin A5 단백질을 인식하는 염소 유래 폴리클로날 항체입니다. IHC(P)에서 3.75 µg/mL 농도로 검증되었습니다. TBS(pH 7.3)와 0.5% BSA로 보존되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DDTVHESAEPSR (aa 189–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933177 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
Ephrin A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases crucial for migration, repulsion, and adhesion during neuronal, vascular, and epithelial development. It binds Eph receptors on adjacent cells, leading to contact-dependent bidirectional signaling.
Forward signaling occurs downstream of the receptor, and reverse signaling occurs downstream of the ephrin ligand. Ephrin A5 signaling requires Fyn tyrosine kinase activity and regulates cell-cell adhesion, cytoskeletal organization, and axon fasciculation. It also plays a role in lens transparency and insulin secretion regulation via interactions with EPHA2, EPHA3, EPHA5, and EPHA7 receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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