Thermo Fisher Scientific Cyclin H Monoclonal Antibody (33TF2-2D4)
Cyclin H 단백질 검출용 Mouse Monoclonal Antibody (Clone 33TF2-2D4). Western blot, Immunoprecipitation, Immunofluorescence에 적합. Human 시료 반응성. 액상 형태, sodium azide 포함, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 | - |
| Immunoprecipitation (IP) | 1:250–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 33TF2-2D4 |
| Immunogen | Synthetic peptide (KKRKGYEDDDYVSKKSKHEE) corresponding to aa 292–311 (C-terminal region) of human cyclin H |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608589 |
Product Specific Information
MA3-025 has been used successfully in Western blotting, Immunoprecipitation, and Immunofluorescence applications to detect Cyclin H in human samples.
Target Information
The protein encoded by this gene belongs to the highly conserved cyclin family, characterized by periodic changes in protein abundance during the cell cycle. Cyclins regulate CDK kinases and exhibit distinct expression and degradation patterns, coordinating mitotic events. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1, functioning as a CDK-activating kinase (CAK). This complex phosphorylates CDK2 and CDC2 kinases and is part of TFIIH and RNA polymerase II complexes, linking transcription regulation with cell cycle control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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