Thermo Fisher Scientific Bovine Activated Protein C Native Protein
소의 활성화된 Protein C 천연 단백질로 면역학적 분석의 양성 대조군으로 사용 가능. SDS-PAGE로 정제된 액상 형태이며, -20°C에서 보관. 혈액 응고 인자 V와 VIII의 활성형을 분해하는 비타민 K 의존성 세린 프로테아제.
- 카테고리
- Protein
- 판매단위
- pk
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Thermo Fisher Scientific Bovine Activated Protein C Native Protein
Applications
- Assay-dependent
Control (Ctrl)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Bovine |
| Molecular Weight | 52.65 kDa |
| Class | Native |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.9 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
RP-43097 contains native bovine Activated Protein C protein.
RP-43097 may be used as a positive control in many immunological assays.
Target Information
Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex.
Activated Protein C contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII.
Protein C is produced in the liver and composed of two polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor, forming an active enzyme (~55 kDa) that cleaves factor Va and VIIIa, inhibiting blood coagulation.
Normal concentrations in human plasma are approximately 1–3 ng/mL for the active enzyme and ~3 µg/mL for the proenzyme.
Mutations in the Protein C gene are associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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