Thermo Fisher Scientific KDELR1 Monoclonal Antibody (KR-10), FITC
KDELR1 단백질을 인식하는 FITC 표지 단일클론 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. 여러 종에 반응하며, 498/517 nm의 형광 특성을 가집니다. 단백질 G로 정제된 액상 형태로 4°C 암소 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Fruit fly, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KR-10 |
| Immunogen | A 21 residue synthetic peptide (amino acids 192–212) based on the bovine KDEL receptor and coupled to KLH |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.09 mM sodium bicarbonate/PBS (pH 7.2) with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931604 |
Additional Formats
- APC (Cat. No. MA5-45149)
- PerCP (Cat. No. MA5-45151)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL was sufficient for detection of KDEL receptor in 20 µg monkey Vero cell lysate by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:AP as the secondary. Detects approximately 25 kDa.
Target Information
KDELR1 (KDEL Endoplasmic Reticulum Protein Retention Receptor 1) is a protein-coding gene. Diseases associated with KDELR1 include Syndromic X-Linked Intellectual Disability 94 and Myopathy, Centronuclear, 1.
Related pathways include Transport to the Golgi and subsequent modification, and Activation of cAMP-Dependent PKA.
Gene Ontology (GO) annotations: ER retention sequence binding and KDEL sequence binding.
An important paralog of this gene is KDELR2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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