Thermo Fisher Scientific Phospho-IRS2 (Ser1100) Polyclonal Antibody
IRS2 단백질의 Ser1100 인산화 상태를 특이적으로 검출하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 사람 및 생쥐 시료 반응성. 고순도 정제된 액상 형태로 안정적이며 연구용으로 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: View publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IRS2 (Accession Q9Y4H2), corresponding to amino acid residues around phosphorylated Ser1100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817493 |
Product Specific Information
Antibody detects endogenous levels of IRS2 only when phosphorylated at Ser1100.
Target Information
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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