Thermo Fisher Scientific FZD10 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 100%

Target Information

FZD10 (Frizzled-10) is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family.
It contains a signal peptide, a cysteine-rich domain in the N-terminal region, seven transmembrane domains, and a C-terminal PDZ domain-binding motif.
FZD10 is involved in signal transduction and intercellular transmission of polarity information during tissue morphogenesis, acting as a receptor for Wnt proteins.

It is highly expressed in placenta, fetal kidney, fetal lung, brain (cerebellum, cerebral cortex, medulla, spinal cord), and shows low expression in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung, and skeletal muscle.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.