Thermo Fisher Scientific SOX10 Recombinant Rabbit Monoclonal Antibody (SN20-41)
SOX10 단백질을 인식하는 recombinant rabbit monoclonal antibody로 높은 특이성과 민감도를 제공. Western blot과 IHC(P) 실험에 적합. Lot 간 일관성 및 동물 유래 성분이 없는 포뮬레이션. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN20-41 |
| Immunogen | Synthetic peptide within Human SOX10 aa 400–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809616 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
SOX10 belongs to the SOX (SRY-related HMG-box) family of transcription factors, which regulate embryonic development and cell fate determination. It acts as a transcriptional activator through complex formation with other proteins and functions as a nucleocytoplasmic shuttle protein. SOX10 is crucial for neural crest and peripheral nervous system development.
Mutations in SOX10 are associated with Waardenburg-Shah and Waardenburg-Hirschsprung diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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