Thermo Fisher Scientific Uteroglobin Monoclonal Antibody (3A8B8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3A8B8

Immunogen

Purified recombinant fragment of human SCGB1A1 (amino acids: 26-91) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Uteroglobin,uniProtId:P11684-1,ncbiNodeId:9606,antigenRange:26-91,antigenLength:91,antigenImageFileName:MA5-17170_Uteroglobin_P11684-1_House_mouse.svg,antigenImageFileNamePDP:MA5-17170_Uteroglobin_P11684-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538641

Product Specific Information

MA5-17170 targets SCGB1A1 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples.

The MA5-17170 immunogen is purified recombinant fragment of human SCGB1A1 (amino acids: 26-91) expressed in E. Coli.

MA5-17170 detects SCGB1A1 which has a predicted molecular weight of approximately 10kDa.

Target Information

Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.