Thermo Fisher Scientific SFTPC Monoclonal Antibody (5E6A9)
Human SFTPC 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 ELISA에 적합합니다. 정제된 재조합 SFTPC(aa 60–180)를 면역원으로 사용하였으며, 단백질 G로 정제된 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E6A9 |
| Immunogen | Purified recombinant fragment of human SFTPC (amino acids: 60–180) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538643 |
Product Specific Information
- MA5-17172 targets SFTPC in indirect ELISA and WB applications and shows reactivity with Human samples.
- Immunogen: purified recombinant fragment of human SFTPC (amino acids 60–180) expressed in E. coli.
- Detects SFTPC with a predicted molecular weight of approximately 21 kDa.
Target Information
SFTPC encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins, including plasma proteins and apolipoproteins SPA, SPB, SPC, and SPD. The surfactant is secreted by alveolar cells of the lung and maintains pulmonary tissue stability by reducing surface tension of fluids that coat the lung.
Mutations in this gene cause pulmonary surfactant metabolism dysfunction type 2 (pulmonary alveolar proteinosis due to surfactant protein C deficiency) and are associated with interstitial lung disease in infants, children, and adults. Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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