Thermo Fisher Scientific c-Myc Oncoprotein Monoclonal Antibody (MYC699)
Thermo Fisher의 c-Myc 단클론 항체(MYC699)는 인간 및 영장류 시료에서 c-Myc 단백질을 검출하는 데 사용됩니다. ICC/IF, Flow Cytometry, ELISA에 적합하며, Protein A/G로 정제된 액상 형태입니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 4609-MSM1-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific c-Myc Oncoprotein Monoclonal Antibody (MYC699)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chimpanzee, Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MYC699 |
| Immunogen | Synthetic peptide corresponding to aa 408–439 (AEEQKLISEEDLLRKRREQLKHKLEQL-RNSCA) from the C-terminus of human c-Myc, coupled to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Mouse.
Target Information
The c-Myc protein is a 62 kDa transcription factor encoded by the c-Myc gene on human chromosome 8q24. It is frequently activated in tumor cells and regulates cellular proliferation, differentiation, apoptosis, and cell cycle progression.
Phosphorylation at Thr58/Ser62 by kinases such as GSK3, CDK, ERK2, and JNK is associated with cell proliferation control.
c-Myc plays a key role in vasculogenesis and angiogenesis during tumor development. Deregulated c-Myc expression can induce apoptosis and is implicated in various cancers including lung, breast, and colon carcinoma, as well as Burkitt’s lymphoma.
Antibodies against c-Myc epitopes can recognize Myc-tagged fusion proteins. Amplification or translocation of the c-Myc gene is observed in multiple tumor types and hematopoietic neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.