Thermo Fisher Scientific Human/Mouse/Rat Activin A Recombinant Protein, PeproTech
Human/Mouse/Rat Activin A 재조합 단백질로, TGF-β 슈퍼패밀리 성장 인자 연구에 사용됩니다. Insect cell 발현, ≥95% 순도, ED50 ≤ 2.0 ng/ml의 높은 생물학적 활성. Lyophilized 형태로 제공되며 -20°C 보관, 실온 배송 가능합니다.
- 카탈로그번호
- 120-14-xxxxx (6개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
6개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human/Mouse/Rat Activin A Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to 106 publications
Miscellaneous PubMed (Misc)
- Refer to 12 publications
Immunostaining (IS)
- Refer to 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human, Mouse, Rat |
| Published Species | Amphibian, Bovine, Chicken, Human, Mouse, Pig, Rat |
| Expression System | Insect cells |
| Amino Acid Sequence | GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS |
| Molecular Weight | 26 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥95% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Inhibits proliferation of mouse MPC-11 cells; ED50 ≤ 2.0 ng/ml (≥5×10⁵ units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
- Catalog No. 120-14-1MG is provided as 2 × 500 µg (120-14-500UG).
- Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues.
- Shipped at ambient temperature. For storage, handling, and reconstitution details, refer to the lot-specific Certificate of Analysis.
Target Information
Activins are dimeric growth and differentiation factors belonging to the transforming growth factor-beta (TGF-β) superfamily. They signal through a heteromeric complex of receptor serine kinases, including at least two type I (I, IB) and two type II (II, IIB) receptors. These receptors are transmembrane proteins composed of:
- Ligand-binding extracellular domain with cysteine-rich region
- Transmembrane domain
- Cytoplasmic domain with serine/threonine kinase activity
Type I receptors are essential for signaling, while type II receptors are required for ligand binding and type I receptor expression. Upon ligand binding, type I and II receptors form a stable complex, leading to phosphorylation of type I receptors by type II receptors. Mutations in Activin A are associated with fibrodysplasia ossificans progressiva.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.