Thermo Fisher Scientific CYBA Polyclonal Antibody
Rabbit polyclonal antibody targeting human CYBA (p22phox), validated for WB and IHC applications. Antigen affinity purified, supplied as liquid at 0.1 mg/mL in PBS with glycerol. Ideal for studying NADPH oxidase complex and chronic granulomatous diseas...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human p22phox. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735694 |
Product Specific Information
- Positive Control: K562, THP-1, HL-60
- Predicted Reactivity: Dog (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), characterized by the failure of activated phagocytes to generate superoxide, which is essential for microbicidal activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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