Thermo Fisher Scientific TSLP Polyclonal Antibody
인간 TSLP 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human TSLP (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736757 |
Product Specific Information
- Positive Control: Human kidney
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TSLP (Thymic Stromal Lymphopoietin) is a 159 amino acid four-helix bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the TSLP receptor and the IL-7R alpha-chain.
It influences myeloid cells, induces T cell-attracting chemokines from monocytes, and enhances the maturation of dendritic cells and T cells into proallergic effectors.
TSLP primes dendritic cells to produce IL-12 after CD40 ligand stimulation, regulates the selection of regulatory T cells, and maintains peripheral CD4 (+) T cell homeostasis.
It also induces allergic inflammation by activating mast cells and may play a role in inflammatory arthritis.
TSLP expression is observed in heart, liver, and prostate tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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