Thermo Fisher Scientific LZTR2 Polyclonal Antibody
Human 및 Mouse 반응성을 가진 LZTR2 폴리클로날 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human LZTR2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 0.1M glycine, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736108 |
Product Specific Information
- Predicted Reactivity: Human (100%), Rat (84%), Rabbit (90%), Bovine (92%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and functions as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene.
LZTR2 is primarily cytoplasmic but may translocate to the nucleus via protein kinase C signaling upon hormonal stimulation.
Recent studies suggest correlations between LZTR2 single nucleotide polymorphisms (SNPs) and obesity in the Japanese population, similar to associations observed with TMEM18, GNPDA2, BDNF, FAIM2, and MC4R genes in Caucasian populations, implying a potential role in metabolism and obesity risk.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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