Thermo Fisher Scientific PSRC1 Polyclonal Antibody
PSRC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용에 사용 가능. 인간 및 생쥐 반응성, 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PSRC1 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.86 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736472 |
Product Specific Information
- Positive Control: 293T, A431, human PSRC1-transfected 293T
- Predicted Reactivity: Rhesus Monkey (95%), Bovine (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PSRC1 is required for normal progression through mitosis. It ensures proper chromosome congression at the metaphase plate and normal chromosomal segregation during anaphase. The protein regulates mitotic spindle dynamics, increases microtubule turnover on metaphase spindles, and contributes to tension generation across sister kinetochores. PSRC1 recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles and may play a role in p53/TP53-regulated growth suppression.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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