Thermo Fisher Scientific Cytokeratin 6 (KRT6) (Basal Cell Marker) Monoclonal Antibody (KRT6/1702)
Cytokeratin 6 단백질을 인식하는 단클론 항체로, 인간 및 마우스 시료에 반응합니다. IHC(Paraffin) 및 IHC(PFA) 실험에 적합하며, 고순도의 Protein A/G 정제 항체입니다. 표피 및 상피세포의 분화 및 증식 연구에 유용합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT6/1702 |
| Immunogen | Recombinant human keratin 6 protein (Cytokeratin 6; UniProt IDs: P02538-1, P48668-1, P04259-1; Antigen range: 1–564 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, as well as in the epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with cellular differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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