Thermo Fisher Scientific Thyroglobulin Recombinant Rabbit Monoclonal Antibody (TGB, 1970R)

Applications

• Immunohistochemistry (Paraffin) (IHC (P))

Tested Dilution: 1–2 µg/mL
Publications: N/A

Product Specifications

Product Specific Information

• This antibody does not react with Mouse or Rat.
• For Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
• Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Thyroid disorders are often autoimmune in origin, and anti-thyroglobulin autoantibodies were among the first discovered. Anti-hTG is found in all thyroid autoimmune diseases (e.g., Hashimoto thyroiditis, Graves disease), with the highest levels in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for patient follow-up.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: 7038-RBM10-P0_Thyroglobulin_P01266-1_Rabbit.svg, 7038-RBM10-P0_Thyroglobulin_P01266-1_Rabbit_PDP.jpeg)