Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (r6E1)
인간 Thyroglobulin을 인식하는 단클론 항체로, 갑상선 세포 마커 연구에 적합합니다. IHC(P) 및 IHC(PFA) 실험에 사용 가능하며, Mouse 및 Rat과 반응하지 않습니다. Protein A/G로 정제된 액상 항체로 4°C 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 0.25–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | r6E1 |
| Immunogen | Human thyroid follicular cells (Thyroglobulin, UniProt ID: P01266-1, 1–2768 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Mouse or Rat.
Target Information
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were among the first to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (e.g., Hashimoto thyroiditis, Graves disease), with the highest levels in Hashimoto thyroiditis. It is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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