Thermo Fisher Scientific Phospho-GAB2 (Tyr452) Polyclonal Antibody
Phospho-GAB2 (Tyr452) 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 보존제를 포함하지 않고 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr452 of human Gab2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977875 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene belongs to the GRB2-associated binding protein (GAB) family. These proteins contain a pleckstrin homology (PH) domain and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They function as adapters transmitting signals in response to cytokine and growth factor receptor stimulation, as well as T- and B-cell antigen receptor activation. The encoded protein is a principal activator of phosphatidylinositol-3 kinase in response to high-affinity IgE receptor activation. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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