Thermo Fisher Scientific GNAQ Polyclonal Antibody
다양한 종에서 반응하는 Rabbit Polyclonal GNAQ 항체로 Western blot, IHC, IP 등에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 고농도(180 µg/mL)로 제공. 세포 신호전달 연구용으로 적합하며 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues of human guanine nucleotide-binding protein Ga (q) subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 180 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979216 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit, resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits can regulate various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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