
Thermo Fisher Scientific LINGO1 Polyclonal Antibody
LINGO1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 검증 완료. 다양한 종에 반응하며 항원 친화 크로마토그래피로 정제됨. 액상 형태, 1 mg/mL 농도. 신경 재생 및 수초화 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from C-terminus of human LINGO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550359 |
Product Specific Information
- Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Elephant, Panda, Horse, Rabbit, Pig (100%).
- For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for inhibition of axonal regeneration by myelin-associated factors. It also acts as a negative regulator of oligodendrocyte differentiation and axonal myelination. LINGO1 functions with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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