Thermo Fisher Scientific Phospho-PKMYT1 (Ser83) Polyclonal Antibody
PKMYT1 단백질의 Ser83 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(파라핀) 분석에 적합. 고순도 정제 및 안정한 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PKMYT1 (Accession Q99640), corresponding to amino acid residues around phosphorylated Ser83. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816093 |
Product Specific Information
This antibody detects endogenous levels of Myt1 only when phosphorylated at Ser83.
Target Information
PKMYT1 serine/threonine kinase is a member of a family of neural-specific, zinc finger-containing DNA-binding proteins that bind to promoter regions of proteolipid proteins in the central nervous system and play a role in neural development. MYT1, along with a closely related CCHC zinc finger protein, is expressed in developing neurons. Recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bind the same cis-regulatory element in the PLP1 promoter in vitro, with DNA binding dependent on Zn²⁺ but not other divalent cations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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