Thermo Fisher Scientific Phospho-PKMYT1 (Ser83) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human PKMYT1(Accession Q99640), corresponding to amino acid residues around phosphorylated Ser83. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PKMYT1,uniProtId:Q99640-1,ncbiNodeId:9606,antigenRange:83,antigenLength:499,antigenImageFileName:PA5-104618_PKMYT1_Q99640-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104618_PKMYT1_Q99640-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816093

Product Specific Information

Antibody detects endogenous levels of Myt1 only when phosphorylated at Ser83.

Target Information

PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.