Thermo Fisher Scientific CD137/4-1BB/TNFRSF9 Monoclonal Antibody (r4-1BB/4603)
CD137/4-1BB/TNFRSF9 단클론 항체로 인간 시료에 반응. 활성화된 T세포 표지자 연구에 적합하며, IHC(P) 및 IHC(PFA) 응용 가능. 단백질 A/G 정제, 1 mg/mL 농도, PBS 버퍼에 보존. 연구용 전용 제품.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | r4-1BB/4603 |
| Immunogen | Recombinant fragment (aa 19–188) of human CD137 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137 (also known as TNFRSF9 or 4-1BB) is an inducible costimulatory molecule expressed mainly on activated T cells.
Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
CD137 signaling maintains survival of activated and memory CD8+ T cells, promotes clonal expansion, and regulates cytokine release affecting monocyte survival.
Soluble CD137 may act as a negative regulator in immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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