Thermo Fisher Scientific CD137/4-1BB/TNFRSF9 Monoclonal Antibody (4-1BB/3201), Biotin
인간 CD137/4-1BB/TNFRSF9 인식 단일클론 항체로 Biotin 결합형입니다. 다양한 면역분석(WB, IHC, ICC, Flow, ELISA 등)에 사용 가능하며, 고순도 Protein A/G 정제 제품입니다. PBS 버퍼 내 안정화되어 4°C 암조건에서 보관합니다.
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Thermo Fisher Scientific CD137/4-1BB/TNFRSF9 Monoclonal Antibody (4-1BB/3201), Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 2–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4-1BB/3201 |
| Immunogen | Recombinant fragment (aa 19–188) of human CD137/4-1BB/TNFRSF9 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137 (also known as TNFRSF9 or 4-1BB) is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling supports survival and clonal expansion of activated and memory T cells while regulating myelopoiesis and dendritic cell development. Activated CD137 induces cytokine release that modulates peripheral monocyte survival. Soluble CD137 may act as a negative regulator of immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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