Thermo Fisher Scientific MADCAM1 Monoclonal Antibody (OTI1C4), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:4,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues.
It belongs to the immunoglobulin family and is similar to ICAM1 and VCAM1.
At least seven alternatively spliced transcripts encoding different protein isoforms have been identified, though some full-length variants remain undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.