Thermo Fisher Scientific Human TPO (Thrombopoietin) Recombinant Protein, PeproTech
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| 카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
| 300-18-1MG | - | Thermo Fisher Scientific 300-18-1MG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 1 mg pk | 재고문의 | pk | 6,809,000원 | - | 7,489,900원 | |
| 300-18-500UG | - | Thermo Fisher Scientific 300-18-500UG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 500 ug pk | 재고문의 | pk | 4,140,000원 | - | 4,554,000원 | |
| 300-18-250UG | - | Thermo Fisher Scientific 300-18-250UG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 250 ug pk | 재고문의 | pk | 2,479,000원 | - | 2,726,900원 | |
| 300-18-100UG | - | Thermo Fisher Scientific 300-18-100UG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 100 ug pk | 재고문의 | pk | 1,483,000원 | - | 1,631,300원 | |
| 300-18-50UG | - | Thermo Fisher Scientific 300-18-50UG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 50 ug pk | 재고문의 | pk | 952,000원 | - | 1,047,200원 | |
| 300-18-10UG | - | Thermo Fisher Scientific 300-18-10UG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 10 ug pk | 재고문의 | pk | 311,000원 | - | 342,100원 | |
| 300-18-2UG | - | Thermo Fisher Scientific 300-18-2UG Human TPO (Thrombopoietin) Recombinant Protein, PeproTech 2 ug pk | 재고문의 | pk | 139,000원 | - | 152,900원 | |
Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
ELISA (ELISA)
Assay-dependent
Neutralization (Neu)
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View 1 publication 1 publication
Functional Assay (Functional)
Assay-dependent
In vitro Assay (IV)
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View 352 publications 352 publications
Miscellaneous PubMed (Misc)
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View 34 publications 34 publications
Product Specifications
Species
Human
Published species
Hamster, Human, Mouse, Non-human primate, Rat, Virus
Expression System
E. coli
Amino acid sequence
SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL
Molecular weight
18.6 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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