Thermo Fisher Scientific IL3RA/CD123 (Acute Myeloid Leukemia Marker) Monoclonal Antibody (IL3RA/2065)

Applications

Tested Dilution

Publications

ELISA (ELISA)

2-4 µg/mL

-

Peptide Array (Array)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

IL3RA/2065

Immunogen

Recombinant human IL3RA protein fragment (around aa 26-171). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD123,uniProtId:P26951-1,ncbiNodeId:9606,antigenRange:26-171,antigenLength:378,antigenImageFileName:3563-MSM3-P1ABX_CD123_P26951-1_House_mouse.svg,antigenImageFileNamePDP:3563-MSM3-P1ABX_CD123_P26951-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.