Thermo Fisher Scientific DNM1L Recombinant Rabbit Monoclonal Antibody (2H15L40)
DNM1L 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 Immunocytochemistry에 최적화됨. 높은 특이성과 일관된 로트 간 재현성을 제공하며, 인간, 마우스, 랫트 시료에 반응. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2H15L40 |
| Immunogen | Peptides corresponding to human DNM1L (aa406–aa423, aa443–aa458) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2723081 |
Product Specific Information
This antibody is predicted to react with Monkey and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The human dynamin-related protein DRP1 contributes to mitochondrial division in mammalian cells. It plays a critical role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, providing a genetic tool to study mitochondrial function in synaptic activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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