Thermo Fisher Scientific Parkin Recombinant Rabbit Monoclonal Antibody (21H24L9)
Parkin 단백질을 인식하는 재조합 토끼 단클론 항체로, 인간, 생쥐, 랫트에 반응합니다. Western blot 및 IP에 적합하며, 높은 특이성과 일관성을 제공합니다. 단백질 A로 정제된 액상 형태로, 4°C 보관 시 안정적입니다.
- 카탈로그번호
- 702785
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2.5 µg/mL | View 4 publications |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 21H24L9 |
| Immunogen | Protein corresponding to human Parkin (aa 1–465) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2724937 |
Additional Formats
Product Specific Information
This antibody is predicted to react with Monkey, Rat, Pig, and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Parkin is part of a multiprotein E3 ubiquitin ligase complex that mediates proteasomal degradation of substrate proteins. Mutations in the Parkin gene are associated with Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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