Thermo Fisher Scientific IDH1 Monoclonal Antibody (A11-B4)
IDH1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(파라핀) 실험에 최적화됨. 인간 및 제브라피쉬에 반응하며, 비결합형 액상 형태로 제공. 단백질 A로 정제되어 높은 순도와 재현성을 보장.
- 카탈로그번호
- MA541084
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Zebrafish |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A11-B4 |
| Immunogen | Recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898838 |
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizes NAD(+) and the other NADP(+). Five isocitrate dehydrogenases have been reported — three NAD(+)-dependent (mitochondrial) and two NADP(+)-dependent (one mitochondrial, one cytosolic).
The NADP(+)-dependent cytoplasmic enzyme contains a PTS-1 peroxisomal targeting signal and plays a role in NADPH regeneration for intraperoxisomal reductions and cytoplasmic NADPH production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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