Thermo Fisher Scientific Human Osteopontin Recombinant Protein, PeproTech
인간 Osteopontin 재조합 단백질로 세포 부착 및 기능성 분석에 사용됩니다. HEK293 세포에서 발현되며 ≥97% 순도와 낮은 엔도톡신 수준을 가집니다. 세포 이동, 염증, 골형성 연구에 적합합니다. 동결건조 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- 120-35-xxx (6개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
6개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Osteopontin Recombinant Protein, PeproTech
Applications
Western Blot (WB)
- Assay-dependent
ELISA
- Assay-dependent
Functional Assay
- Assay-dependent
In vitro Assay
- Assay-dependent
- View 8 publications
Miscellaneous PubMed
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | HEK293 cells |
| Amino Acid Sequence | IPVKQADSGS SEEKQLYNKY PDAVATWLNP DPSQKQNLLA PQNAVSSEET NDFKQETLPS KSNESHDHMD DMDDEDDDDH VDSQDSIDSN DSDDVDDTDD SHQSDESHHS DESDELVTDF PTDLPATEVF TPVVPTVDTY DGRGDSVVYG LRSKSKKFRR PDIQYPDATD EDITSHMESE ELNGAYKAIP VAQDLNAPSD WDSRGKDSYE TSQLDDQSAE THSHKQSRLY KRKANDESNE HSDVIDSQEL SKVSREFHSH EFHSHEDMLV VDPKSKEEDK HLKFRISHEL DSASSEVN |
| Molecular Weight | 33.7 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥97% by SDS-PAGE and HPLC |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Enhances cell adhesion of murine B16-F1 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant human Osteopontin is a 298 amino acid protein that migrates at an apparent molecular weight of 60.0–65.0 kDa by SDS-PAGE under reducing conditions due to glycosylation.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It plays roles in bone mineralization, cell adhesion, migration, chronic inflammatory diseases, and transformation processes.
Proteolytic cleavage by thrombin and matrix metalloproteinases near the RGD sequence modulates its function and integrin binding properties. Thrombin-cleaved fragments are overexpressed in malignant glial tumors, providing a survival advantage and serving as substrates for plasmin and cathepsin D.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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