Thermo Fisher Scientific TRIM23 Monoclonal Antibody (2H4)
TRIM23 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot과 ELISA에 사용 가능. 인간 시료에 반응하며, E3 유비퀴틴 리가아제 활성 연구에 적합. PBS 버퍼에 보존되어 있으며, -20°C에서 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H4 |
| Immunogen | TRIM23 (AAH22510, 1–110 a.a.) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY
Target Information
Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in Lys-63-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection.
The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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