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Thermo Fisher Scientific TRIM23 Monoclonal Antibody (3E8)
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인간 TRIM23 단백질을 인식하는 Mouse IgG2a 단클론 항체. Western blot과 ELISA에 최적화되어 있으며, 고순도 친화 크로마토그래피 정제 제품. 액상 형태로 제공되며, -20°C에서 보관 권장.
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Thermo Fisher Scientific H00000373-M05 TRIM23 Monoclonal Antibody (3E8) 100 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific TRIM23 Monoclonal Antibody (3E8)
Thermo Fisher Scientific TRIM23 Monoclonal Antibody (3E8)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E8 |
| Immunogen | TRIM23 (AAH22510, 1–110 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of TRIM23 protein (partial):
MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL
CGHTVCHDCL TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQYTarget Information
Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in Lys-63-linked auto-ubiquitination of TRAF6, resulting in virally controlled activation of NF-kappa-B during early infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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