
Thermo Fisher Scientific DCC Monoclonal Antibody (OTI4A1), TrueMAB
DCC 단백질을 인식하는 마우스 모노클로날 항체로 Western blot에 적합합니다. 인간 시료에 반응하며, TrueMAB 포맷으로 높은 특이성과 재현성을 제공합니다. 액상 형태로 제공되며, PBS/BSA/glycerol 완충액에 보관됩니다.
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Applications
- Western Blot (WB): 1:200 희석 비율로 테스트됨
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A1 |
| Immunogen | Full length human recombinant protein of human DCC produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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