Thermo Fisher Scientific CD97 Monoclonal Antibody (MEM-180), FITC
인간 CD97 단백질을 인식하는 FITC 결합 단클론 항체로, 활성화된 B/T 세포 및 단핵세포 분석에 적합. Flow cytometry용으로 검증됨. 액상 형태로 제공되며 PBS/BSA 완충액에 보관. 4°C 암소 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 20 µL x 100 µL whole blood or 10^6 cells
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-180 |
| Immunogen | PHA-activated PBL |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073511 |
Product Specific Information
This antibody recognizes a unique epitope on CD97, a 75–85 kDa surface glycoprotein of the G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells, and granulocytes.
Target Information
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor constitutively expressed on granulocytes and monocytes, and rapidly upregulated on T and B cells upon activation.
It is produced in alternatively spliced forms and interacts with CD55 (DAF), which protects cells from complement-mediated damage.
CD97–CD55 interaction facilitates leukocyte activation and migration, and CD97 may play roles in tumor migration and invasiveness, T cell regulation, and peripheral granulocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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