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Thermo Fisher Scientific NEDD4L Polyclonal Antibody
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Thermo Fisher Scientific의 NEDD4L Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 토끼 유래 IgG 항체입니다. Western blot과 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 10:52
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Thermo Fisher Scientific A302514A NEDD4L Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
658,900원VAT 포함 724,790원
Thermo Fisher Scientific · Thermo Fisher Scientific NEDD4L Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 and 475 of human neural precursor cell expressed, developmentally down-regulated 4-like |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
NEDD4L is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 enzyme and transfers it to target substrates. It inhibits TGF-beta signaling by promoting ubiquitination and proteasome-dependent degradation of SMAD2 and TGFR1. NEDD4L also mediates ubiquitination and internalization of plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1, and CLC5, as well as degradation of SGK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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