Thermo Fisher Scientific SSA1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Sjogren syndrome antigen A1 (TRIM21). Validated for Western blot and immunoprecipitation. Unconjugated, liquid form, 0.20 mg/mL concentration. Recommended storage at 4°C and shelf life of 1 year.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- Publications: [References not provided]
Immunoprecipitation (IP)
- Tested Dilution: 5–15 µg/mg lysate
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 and 475 of Human Sjogren syndrome antigen A1 (TRIM21, UniProt ID: P19474-1, NCBI Node ID: 9606) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (RING, B-box type 1, and B-box type 2) and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein complex, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described, but only one full-length form has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: A302-519A-M_TRIM21_P19474-1_Rabbit.svg, A302-519A-M_TRIM21_P19474-1_Rabbit_PDP.jpeg)
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