Thermo Fisher Scientific Kininogen Precursor Monoclonal Antibody (24F9)
인간 혈장 유래 단백질을 면역원으로 한 Mouse IgG monoclonal antibody. Western blot, ICC/IF, ELISA에 사용 가능. 고분자 및 저분자 키니노겐 검출에 적합하며, 혈액 응고 및 칼리크레인-키닌 시스템 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 24F9 |
| Immunogen | Protein purified from Human plasma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1957750 |
Product Specific Information
A suggested positive control for this product is human plasma.
Target Information
This gene uses alternative splicing to generate two different proteins — high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK).
HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Bradykinin, a peptide causing numerous physiological effects, is released from HMWK.
In contrast, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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