Thermo Fisher Scientific Lamin B1 Monoclonal Antibody (L-5)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

View 57 publications 57 publications

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

5-10 µg/mL

View 1 publication 1 publication

ELISA (ELISA)

0.1-1.0 µg/mL

-

Immunoprecipitation (IP)

2.5-5 µg

View 2 publications 2 publications

in situ PLA (PLA)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 5 publications 5 publications

Product Specifications

Species Reactivity

Chicken, Human, Mouse, Rat

Published species

Dog, Human, Mouse, Non-human primate, Pig, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

L-5

Immunogen

Extracts from chicken nuclei if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Lamin B1,uniProtId:P14731-1,ncbiNodeId:9031,antigenRange:1-584,antigenLength:584,antigenImageFileName:33-2000_Lamin_B1_P14731-1_House_mouse.svg,antigenImageFileNamePDP:33-2000_Lamin_B1_P14731-1_House_mouse_PDP.jpeg,sortOrder:4}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533106

Target Information

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Defects in the LMNB1 gene can cause Leukodystrophy, demyelinating, autosomal dominant, adult-onset (ADLD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.